I-TASSER (Iterative Threading ASSEmbly Refinement)

"I-TASSER server is an on-line platform for protein structure and function predictions. It allows academic users to automatically generate high-quality predictions of 3D structure and biological function of protein molecules from their amino acid sequences. I-TASSER (as 'Zhang-Server') was ranked as the No 1 server for protein structure prediction in recent community-wide CASP7, CASP8, CASP9, CASP10, and CASP11 experiments. It was also ranked as the best for function prediction in CASP9. The server is in active development with the goal to provide the most accurate structural and function predictions using state-of-the-art algorithms. The server is only for non-commercial use." - from website